Jason McCreary gives an overview of what “WordPress Multitenancy” is and the steps he took to achieve it, along with his current working solution.

http://jason.pureconcepts.net/2012/08/wordpress-multitenancy/

This is relevant to servers hosting a number of WordPress installs. Having a shared core codebase (not necessarily using multisite) means it’s easier to detect changes in the codebase by having it version controlled. Also less shared memory will be needed by the APC opcode cache, giving you more memory for object caching etc.

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